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DNA Methylation and Cancer Therapy
NA methylation has bewildered molecular biologists since Hotchkiss discovered it almost six decades ago (Hotchkiss RDJ. Biol Cem 1948; 175:315-332). The fact that the chemical structure of our D genome consists of two components that are covalently bound, the genetic information that is replicated b...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer US : Imprint: Springer,
2005.
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| Edición: | 1st ed. 2005. |
| Colección: | Medical Intelligence Unit
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| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- DNA Methylation
- Epigenetic Mechanisms of Gene Regulation
- DNA Hypo- vs. Hypermethylation in Cancer
- DNA Methylation in Urological Cancers
- DNA Methylation in Colorectal Cancer
- CpG Island Hypermethylation of Tumor Suppressor Genes in Human Cancer
- The Loss of Methyl Groups in DNA of Tumor Cells and Tissues
- Identifying Clinicopathological Association of DNA Hypermethylation in Cancers Using CpG Island Microarrays
- Methylation Analysis in Cancer
- Regulation of DNA Methyltransferases in Cancer
- Inhibition of Poly(ADP-Ribosyl)ation Allows DNA Hypermethylation
- The Role of Active Demethylation in Cancer and Its Therapeutic Potential
- Purine Analogues and Their Role in Methylation and Cancer Chemotherapy
- DNA Methyltransferase Inhibitors
- Preclinical and Clinical Studies on 5-Aza-2?-Deoxycytidine, a Potent Inhibitor of DNA Methylation, in Cancer Therapy
- Anticancer Gene Therapy by in Vivo DNA Electrotransfer of MBD2 Antisense
- Epilogue.