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Alzheimer's Disease: Cellular and Molecular Aspects of Amyloid beta

This book contains a survey of present-day research into the biomedical fundamentals of Alzheimer's disease (AD). It contains 20 chapters dealing with widely ranging topics, all of which have a bearing upon the understanding and treatment of AD. Starting with a broad survey of the contribution...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Harris, J. Robin (Editor ), Fahrenholz, Falk (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer US : Imprint: Springer, 2005.
Edición:1st ed. 2005.
Colección:Subcellular Biochemistry, 38
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • The Contribution of Microscopy to the Study of Alzheimer's Disease, Amyloid Plaques and A? Fibrillogenesis
  • Transgenic Mouse Models for APP Processing and Alzheimer's Disease: Early and Late Defects
  • Oxidative stress in Alzheimer's Disease: Implications for Prevention and Therapy
  • ?-Secretase, APP and A? in Alzheimer's Disease
  • The Non-Amyloidogenic Pathway: Structure and Function of ?-Secretases
  • Amyloid ? Degradation: A Challenging Task for Brain Peptidases
  • The Protective Role of Vitamin E in Vascular Amyloid ?-Mediated Damage
  • Amyloid Accumulation and Pathogensis of Alzheimer's Disease: Significance of Monomeric, Oligomeric and Fibrillar A?
  • Cholesterol and Amyloid ? Fibrillogenesis
  • Alzheimer's ?-Amyloid: Insights into Fibril Formation and Structure from Congo Red Binding
  • The Aluminium-Amyloid Cascade Hypothesis and Alzheimer's Disease
  • Amyloid-? Metal Interaction and Metal Chelation
  • The Interaction of Amyloid-? with ApoE
  • Clusterin and Alzheimer's Disease
  • Acetylcholinesterase Interaction with Alzheimer Amyloid ?
  • Membrane Disordering Effects of ?-Amyloid Peptides
  • The Role of Alzheimer A? Peptides in Ion Transport Across Cell Membranes
  • Amyloid Inhibitors and ?-Sheet Breakers
  • Cholesterol and Alzheimer's Disease: Statins, Cholesterol Depletion in APP Processing and A? Generation
  • Phosphorylated Amyloid-?: the Toxic Intermediate in Alzheimer's Disease Neurodegeneration.