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Thrombin Physiology and Disease /

It has become increasingly evident in recent years that, apart from the key role that thrombin plays in the blood coagulation cascade, thrombin also elicits cellular actions via the activation of proteinase-activated receptors, which are present in many cell types. These effects of thrombin are seen...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Maragoudakis, Michael E. (Editor ), Tsopanoglou, Nikos E. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2009.
Edición:1st ed. 2009.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Thrombin: Structure, Functions, and Regulation
  • Thrombin: To PAR or Not to PAR, and the Regulation of Inflammation
  • Regulation of Thrombin Receptor Signaling
  • Thrombin-Activated Protein C: Integrated to Regulate Vascular Physiology
  • The Role of Thrombin in Vascular Development
  • The Role of Thrombin in Angiogenesis
  • Thrombin and Thrombin Peptides in Wound Healing and Tissue Repair
  • The Role of Thrombin and Thrombin Receptors in the Brain
  • The Role of Thrombin in Tumor Biology
  • The Role of Thrombin and its Receptors in Epithelial Malignancies: Lessons from a Transgenic Mouse Model and Transcriptional Regulation
  • Anti-thrombotic Therapy in Cancer Patients
  • Thrombin Receptor Modulators: Medicinal Chemistry, Biological Evaluation, and Clinical Application
  • Novel Anticoagulant Therapy: Principle and Practice.