Structure and mechanism in protein science : a guide to enzyme catalysis and protein folding /

Detalles Bibliográficos
Clasificación:QD431.25 S8.5 F4.7b
Autor principal: Fersht, Alan, 1943- (autor)
Formato: Libro
Idioma:Inglés
Publicado: New Jersey : World Scientific, 2017.
Colección:Series in structural biology ; 9
Temas:
Proteins > Mechanism of action
Proteins > Conformation
Catalysis
Enzyme kinetics
Proteínas > Mecanismo de acción
Proteínas > Conformación
Catálisis
Enzimas > Cinética
Tabla de Contenidos:
  • 1. The three-dimensional structure of proteins
  • 2. Chemical catalysis
  • 3. The basic equations of enzyme kinetics
  • 4. Measurement and magnitude of individual rate constants
  • 5. The pH dependence of enzyme catalysis
  • 6. Practical methods for kinetics and equilibria
  • 7. Detection of intermediates in enzymatic reactions
  • 8. Stereochemistry of enzymatic reactions
  • 9. Active-site-directed and enzyme-activated irreversible inhibitors : "affinity labels" and "suicide inhibitors"
  • 10. Conformational change, allosteric regulation, motors, and work
  • 11. Forces between molecules, and binding energies
  • 12. Enzyme-substrate complementarity and the use of binding energy in catalysis
  • 13. Specificity and editing mechanisms
  • 14. Recombinant DNA technology
  • 15. Protein engineering
  • 16. Case studies of enzyme structure and mechanism
  • 17. Protein stability
  • 18. Kinetics of protein folding
  • 19. Folding pathways and energy landscapes.

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