Introduction to proteins : structure, function, and motion /
El libro tiene como objetivo proporcionar al lector una descripción detallada de la estructura de proteínas y la dinámica, combinada con una discusión en profundidad de la relación entre estos dos aspectos y función de las proteínas. Adoptando el enfoque estructural-biofísico, discutimos estos en re...
Clasificación: | QP551 K4.77 |
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Autor principal: | |
Otros Autores: | |
Formato: | Libro |
Idioma: | Inglés Español |
Publicado: |
Boca Raton, Fl. :
CRC Press/Taylor & Francis,
2011.
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Colección: | Chapman & Hall/CRC mathematical and computational biology series
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Temas: |
Tabla de Contenidos:
- Cap. I. Introduction
- The importance of proteins in living organisms
- Structural complexity and its effect on protein function
- Non-covalent interactions between atoms in biomolecules
- Cap. II. Protein structure
- Introduction
- Primary structure
- Secondary structure
- Teriary structure
- Quaternary structure
- Post-translational modifications
- Cap. III. Methods of structure determination and prediction
- Diffraction/scattering methods
- Spectrosopic methods
- Computational methods for structure prediction
- Conclusions
- Protein data bank (PDB)
- Cap. IV. Energetics adn protein stability
- Basic principles of thermodynamics
- Protein stability and the forces involved
- Protein denaturation and adaptation to extreme conditions
- Stability enhancement of industrial enzymes using protein engineering
- Cap. V. Protein structural dynamics
- Protein folding
- Folded state dynamics
- Methods for studying protein dynamics
- Cap. VI. Non-Globular proteins
- Fibrous proteins
- Intrinsically unstructured proteins
- Cap. VII. Membrane proteins
- Structure and organization of biological membranes
- Principles of membrance protein structure
- Protein-membrane interactions
- Structure-function relationship in membrane proteins and peptides
- Cap. VIII. Membrane proteins
- Theories on protein-ligand binding
- Protein-ligand binding energetics
- The lignand-binding site
- protein-protein interactions
- The ligand-protein interactions in drug action and design.