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Introduction to proteins : structure, function, and motion /

El libro tiene como objetivo proporcionar al lector una descripción detallada de la estructura de proteínas y la dinámica, combinada con una discusión en profundidad de la relación entre estos dos aspectos y función de las proteínas. Adoptando el enfoque estructural-biofísico, discutimos estos en re...

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Detalles Bibliográficos
Clasificación:QP551 K4.77
Autor principal: Kessel, Amit
Otros Autores: Ben-Tal, Nir (coaut)
Formato: Libro
Idioma:Inglés
Español
Publicado: Boca Raton, Fl. : CRC Press/Taylor & Francis, 2011.
Colección:Chapman & Hall/CRC mathematical and computational biology series
Temas:
Tabla de Contenidos:
  • Cap. I. Introduction
  • The importance of proteins in living organisms
  • Structural complexity and its effect on protein function
  • Non-covalent interactions between atoms in biomolecules
  • Cap. II. Protein structure
  • Introduction
  • Primary structure
  • Secondary structure
  • Teriary structure
  • Quaternary structure
  • Post-translational modifications
  • Cap. III. Methods of structure determination and prediction
  • Diffraction/scattering methods
  • Spectrosopic methods
  • Computational methods for structure prediction
  • Conclusions
  • Protein data bank (PDB)
  • Cap. IV. Energetics adn protein stability
  • Basic principles of thermodynamics
  • Protein stability and the forces involved
  • Protein denaturation and adaptation to extreme conditions
  • Stability enhancement of industrial enzymes using protein engineering
  • Cap. V. Protein structural dynamics
  • Protein folding
  • Folded state dynamics
  • Methods for studying protein dynamics
  • Cap. VI. Non-Globular proteins
  • Fibrous proteins
  • Intrinsically unstructured proteins
  • Cap. VII. Membrane proteins
  • Structure and organization of biological membranes
  • Principles of membrance protein structure
  • Protein-membrane interactions
  • Structure-function relationship in membrane proteins and peptides
  • Cap. VIII. Membrane proteins
  • Theories on protein-ligand binding
  • Protein-ligand binding energetics
  • The lignand-binding site
  • protein-protein interactions
  • The ligand-protein interactions in drug action and design.